Patients

The Corona Test process for IVF/ISCI

If you’re having trouble becoming pregnant, in vitro fertilisation (IVF) may be right for you and so might also the Corona Test. An IVF cycle involves several different steps that will help you increase the chances of becoming pregnant. The most important step is selecting the embryo with the highest potential to result in the birth of a healthy baby.

  • You will receive hormone stimulation to mature many eggs
  • After egg collection, the embryologist removes the corona cells surrounding the egg to free the egg for sperm injection (ISCI).
  • The successfully fertilised eggs (now called embryos) grow in the laboratory incubator for 3 to 5 days.
  • In the meantime, the corona cells are analysed with the Corona Test to know which of your eggs has the highest potential to result in a healthy baby
  • Your embryologist will monitor the development of the embryos
  • The embryo that shows good development and a high Corona Test score will be chosen for your first transfer.
  • In conclusion, your pregnancy chances will substantially increase with this test compared to embryo selection with only visual inspection.

Who should use the Corona Test?

  • If you are scheduled for ICSI treatment
  • If you are expected to have many oocytes (>2)

Improving your chances with the Corona Test

  • Our study shows higher pregnancy rates after the first transfer (from 27% to 63% pregnancy rate with single embryo transferred after 3 days of culture, results from UZ Brussel)
  • You will have fewer cycles of IVF treatment (less time and money). Our clinical study showed saving an average of 3 transfer cycles
  • The chance that your first transfer will be successful increases. 55% of the women with Corona Test had a live birth from the first embryo transfer cycle in the clinical trial at UZ Brussel

The Corona Test process for freezing your eggs

When you decide to freeze your eggs for future use, you will have to follow these steps:

  • First, you will receive hormone stimulation to mature many eggs.
  • After egg collection, the embryologist removes the corona cells surrounding the egg to free the egg for freezing.
  • Your clinic will freeze your eggs at -198°C.
  • In the meantime, the corona cells are analysed with the Corona Test to know which of your eggs has the highest potential to result in a healthy baby.
  • If you do not have enough eggs with high potential, you might consider a second or third treatment cycle.
  • When you come back to use your eggs, the embryologist can use this test score to aid in the selection of the embryo to be transferred.